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Targets Recommended: FGFR Antiviral Antibiotic

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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T26240 Surfen dihydrochloride

Aminokinuride dihydrochloride,Aminoquinuride dihydrochloride,NSC-12155,Aminokinuride 2HCl,Aminoquinuride 2HCl

FGFR; Antiviral; Antibiotic Angiogenesis; Immunology/Inflammation; Microbiology/Virology; Tyrosine Kinase/Adaptors
Surfen dihydrochloride (Aminoquinuride dihydrochloride) 是一种有效的硫酸肝素小分子拮抗剂,具有抗菌和抗病毒活性,抑制炭疽致死因子、凝血因子 X 和致死因子。Surfen dihydrochloride 可抑制普通肝素和低分子量肝素的抗凝活性,抑制肝素的硫酸化和肝素裂解酶的降解。Surfen dihydrochloridn 抑制阻断硫酸乙酰肝素介导的 FGF2 结合和信号转导。Surfen 抑制 SEVI 和精液介导的 HIV 1 型感染增强。
T69353 Darexaban maleate

Darexaban maleate is a derivative used in the preparation of inhibitors of activated blood coagulation factor X.
TP2234 coagulation factor II (thrombin) B chain fragment [Homo sapiens]

Others Others
Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a serine protease that converts soluble

化合物

Surfen dihydrochloride
Cat.No: T26240
Synonym: Aminokinuride dihydrochloride,Aminoquinuride dihydrochloride,NSC-12155,Aminokinuride 2HCl,Aminoquinuride 2HCl
Target: FGFR, Antiviral, Antibiotic
Darexaban maleate
Cat.No: T69353
Synonym:
Target:
coagulation factor II (thrombin) B chain fragment [Homo sapiens]
Cat.No: TP2234
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-01101 Coagulation factor X/F10 Protein, Human, Recombinant (His)

FXA,FX,coagulation factor

Human Baculovirus Insect Cells
Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the coagulation cascade and blood clotting, as the first enzyme in the common pathway of thrombus formation. Factor X deficiency is one of the rarest of the inherited coagulation disorders. FX deficiency among the most severe of the rare coagulation defects, typically including hema...
TMPJ-00301 Coagulation Factor X Protein, Human, Recombinant (hFc)

Stuart-Prower factor,Stuart factor,Coa...

Human HEK293 Cells
F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1‑40). Both the intrinsic and extrinsic pathways activate Factor X to Xa, which consists of light (residues 41‑179) and heavy (residues 235‑488) chains linked by a disulfide bond. Coagulation factor X is initially synthesized in the liver. The two chains are formed from a single-chain precursor by the excision of two Arg residue...
TMPJ-00707 Coagulation factor X/F10 Protein, Mouse, Recombinant (His)

Stuart factor,Coagulation factor ...

Mouse HEK293 Cells
Mouse coagulation factor X / F10 a member of the peptidase S1 family. The mature F10 is composed mostly of two EGF-like domains, one Gla gamma-carboxy-glutamate domain and one peptidase S1 domain. Factor Xa is a vitamin K-dependent plasma protease that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. The two chains of F10 are formed from a single-chain precursor by the excision of two Arg residues. A single-chain precursor is initiall...
TMPY-00741 CXCL4 Protein, Human, Recombinant

PF-4,platelet factor 4,SCYB4,CXCL4

Human E. coli
Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils a...

重组蛋白

Coagulation factor X/F10 Protein, Human, Recombinant (His)
Cat.No: TMPY-01101
Species: Human
Expression System: Baculovirus Insect Cells
Coagulation Factor X Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00301
Species: Human
Expression System: HEK293 Cells
Coagulation factor X/F10 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00707
Species: Mouse
Expression System: HEK293 Cells
CXCL4 Protein, Human, Recombinant
Cat.No: TMPY-00741
Species: Human
Expression System: E. coli
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